Teaching Faculties
Dr. Ankit Srivastava
Associate Professor (Research Track) Department of Biotechnology and Chemical Engineering
- ankit.srivastava@jaipur.manipal.edu
- Ph.D (Biological Sciences) Indian Institute of Technology Delhi (IIT Delhi) 2017
- B.Tech (Biotechnology) Vellore Institute of Technology (VIT) Vellore 2009
- Diagnostic Assays
- Neurodegeneration
- Parkinson's disease
- Alzheimer's disease
- Protein Misfolding
- Amyloid Aggregation
- Biologics and Drug Discovery for Neurological & Systemic Disorders
- Intramural Research Training Award,
- National Institutes of Allergy & Infectious Diseases (NIAID), NIH, USA,
- Distinction in doctoral studies award,
- Indian Institute of Technology Delhi, 2017, I
- CMR Doctoral Research Fellowship award by the Indian Council of Medical Research (ICMR) 2010-2015
- Member, International Parkinson and Movement Disorder Society (IPMDS), USA
- Member, American Society for Biochemistry and Molecular Biology (ASBMB), USA
- Member, The Protein Society, USA, Life Member, Indian Biophysical Society, India.
- Srivastava A, Wang Q, Orrù CD, Fernandez M, Compta Y, Ghetti B, Zanusso G, Zou WQ, Caughey B, Beauchemin CAA. Enhanced quantitation of pathological α-synuclein in patient biospecimens by proteopathic seed amplification assays. PloS pathogens. 20(9):e1012554. 2024
- Horne RI, Andrzejewska E, Alam P*, Z. Faidon Brotzakis*, Srivastava A*, Aubert A, Nowinska M, Gregory RC, Staats R, Possenti A, Chia S, Sormanni P, Ghetti B, Caughey B, Knowles TPJ, Vendruscolo M. Discovery of Potent Inhibitors of α-Synuclein Aggregation Using Structure-Based Iterative Learning. Nature Chemical Biology. 20, 634-645, 2024 (*Contributed equally)
- Srivastava A, Singh J, Singh Yadav SPS, Arya P, Kalim F, Rose P, Ashish, Kundu B. The Gelsolin Pathogenic D187N Mutant Exhibits Altered Conformational Stability and Forms Amyloidogenic Oligomers. ACS Biochemistry. 57(16):2359-2372. 2018.
- Srivastava A, Sharma S, Sadanandan S, Gupta Sakshi, Singh J, Gupta S, Haridas V, Kundu B. Modulation of prion polymerization and toxicity by rationally designed peptidomimetics. Biochemical J. 474(1):123-147. 2017.
- Arya P*, Srivastava A*, Vasaikar SV, Mukherjee G, Mishra P, Kundu B. Selective interception of gelsolin amyloidogenic stretch results in conformationally distinct aggregates with reduced toxicity. ACS Chemical Neuroscience. 5(10):982-92. 2014. (*Equal First Authors)
